Optical coherence tomography findings in a case of bilateral diffuse uveal melanocytic proliferation
نویسندگان
چکیده
We present the case of bilateral diffuse uveal melanocytic proliferation (BDUMP) in a 74-year-old man. The patient was referred for unexplained rapidly progressive bilateral visual loss associated with ocular fundus changes. His visual acuity at the first visit was 0.01 in the right eye and 0.02 in the left eye. Fundoscopic examination revealed bilateral irregular and discolored lesions. Fluorescein angiography demonstrated the characteristic mosaic with hyperfluorescent patches. Optical coherence tomography (OCT) revealed widespread disruption of the ellipsoid zone and multiple deposits of an abnormal, highly reflective, confluent material within the subretinal space. Following extensive examinations, a diagnosis of squamous cell lung carcinoma was made in the patient. Our findings suggest that OCT is valuable in the diagnosis of BDUMP.
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High-resolution OCT imaging of RPE degeneration in bilateral diffuse uveal melanocytic proliferation.
Bilateral diffuse uveal melanocytic proliferation is a rare paraneoplastic syndrome that presents with bilateral progressive loss of vision. A 70-year-old woman presented with a 3-month history of progressive, bilateral vision loss. The patient had bilateral, diffuse, shallow, subretinal fluid with patchy, reddish-brown lesions at the level of the retinal pigment epithelium (RPE) that showed si...
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